The Single-Cell and Spatial Playbook

Single-cell and spatial omics are rapidly evolving fields. While single-cell methodologies are beginning to mature into reliable, standardised technologies, spatial biology techniques are exponentially advancing. However, given the fast pace of these developments, fundamental challenges that make it difficult to refine and optimise results are yet to be widely solved. Consequently, for many researchers it can be difficult to achieve the best possible results in their single-cell and spatial experiments.

What if you could get the very latest tips, hints and intelligence on how to get the best results from your single-cell and spatial work?

Introducing The Single-Cell and Spatial Playbook – a novel style of report packed full of unique expert insights, tools and ideas to help you to quickly solve common challenges being faced by the field right now.

From trouble with reproducibility in sample prep, to challenges in proteomics, and standardisation in single-cell and spatial data analysis – our contributors provide advice and solutions for you to takeaway and implement in your work. Here are some of the highlights:

• Julienne L. Carstens (Assistant Professor, University of Alabama at Birmingham) discusses reproducibility in sample preparation, “The issue of reproducibility is exactly why we are required to have both technical and biological replicates to compensate for the noise – biology is messy!".
• Luciano Martelotto (Associate Professor, Head of the Development Laboratory, Adelaide Centre for Epigenetics (ACE), South Australia ImmunoGENomics Cancer Institute) highlights the need for a standard procedure in sample preparation processes, "Having a standard operating procedure makes achieving reproducibility easier. Success is a lot of small things done right”.
• Adam Bryce (Clinical Research Fellow, School of Cancer Sciences, University of Glasgow) explores the translation of single-cell and spatial proteomics to the clinic, “I think things will move from the heavily supervised approach we have now, to a weakly supervised or entirely unsupervised approach aided by AI and ML”.
• Mitro Miihkinen (Senior Researcher in the Aittokallio Group, FIMM, HiLIFE, iCAN, University of Helsinki) offers insights into standardising single-cell and spatial data analysis, "Creating clear guidelines and open-data benchmarks will help set up standard procedures”.

On top of these ‘golden-nuggets’ of advice, The Single-Cell and Spatial Playbook journeys through advancements in the field across the past year to help you keep up-to-date. We hear from researchers working on single-cell and spatial multi-omics, artificial intelligence and machine learning tools, data analysis and translation to the clinical setting.

The best part? The Single-Cell and Spatial Playbook is completely FREE to download. We strongly believe that you should be able to access that helpful advice for your research easily and quickly. So, what are you waiting for? Click the link below to download the report now.